Causes and symptoms of myelofibrosis Though the progress in medical science over the years has eradicated major diseases from the face of the earth, there are certain health conditions that are yet to be completely treated. One such ailment that is invincible till date and continues to claim lives is cancer. Cancer can affect any part of the body and is only treatable when it is diagnosed in its earlier stages. One such form of cancer that affects the bone marrow is called myelofibrosis. Myelofibrosis is that type of bone marrow cancer that affects the body’s ability to produce blood cells. In fact, myelofibrosis is a part of a group of conditions called myeloproliferative neoplasms (MPNs), which cause the bone marrow to stop developing and functioning the way it should. This causes fibrous scar tissue. This form of cancer can be primary (occurs on its own) or secondary (occurs due to some other condition that affects the bone marrow). Moreover, the other MPNs can progress and gradually turn into myelofibrosis over a period of time. Causes of myelofibrosis This condition is caused by a genetic mutation in the blood stem cells. It affects the blood stem cells’ ability to replicate and divide into the multiple specialized cells that make up the blood.

In addition to your skincare and haircare regime, there is something else that needs your attention—dental care. Adding dental care to your daily list of regimes will ensure that you can continue flaunting your pearlies even when you are old. Dental care does not imply simply brushing your teeth or flossing once in a month. There are other practices that ensure that your teeth withstand the onslaught of foods and the aging process. Contrary to what people believe, cavities aren’t the only dental issues that can affect us, there’s plaque, bad breath, yellow teeth, swollen gums, and many more. To ensure that you do not have to suffer such agonizing dental issues, there are certain effective dental care tips that will prove to be incredibly useful in the long run. Brush and floss regularly, twice a day Contrary to your childhood practices, you need to add flossing to your daily dental care regime. People usually brush twice a day to prevent food particles from settling in the nooks and crannies of their mouth. However, simply brushing your teeth won’t get rid of the leftover food stuck in your teeth, which is why you need to floss twice a day as well.

Calcium is one of the major nutrients for our body. It is present in the bones, teeth, nerve cells, body tissue, and blood. Age progression and an imbalanced or malnourished diet can cause calcium deficiency, leading to several diseases such as osteopenia, osteoporosis, and hypocalcemia. As calcium is a crucial mineral for maintaining normal bodily functions such as bone development and stabilization of blood pressure, its deficiency can lead to various deficiency diseases mentioned below: Osteoporosis The term osteoporosis means “porous bones”. It is a progressive bone disease that results in the decline of the bone density and mass, which surges the risk of bone fractures. The calcium deficiency disease is common in post-menopausal women, but it can also affect both men and women above 75 years of age. Other risk factors associated with osteoporosis include lower levels of sex hormones, increasing age, and excessive smoking. Osteoporosis can make bones weak to the extent that they can get fractured even with bending and coughing. Osteopenia Low bone mass or osteopenia can be caused due to depletion in the bone mineral density. Physicians and orthopedics consider osteopenia as the first step toward osteoporosis. The disease is more prevalent in post-menopausal women than men and can cause complications due to lack of exercise, unhealthy lifestyle, overdependence on alcohol, and excessive smoking.

Dry mouth or xerostomia is a condition where the mouth’s salivary glands can’t make enough saliva. Apart from the unpleasant dry feeling in the mouth, this condition can cause trouble while chewing and swallowing food, bad breath, loss of taste buds, and a sore throat. Dry mouth can be a consequence of aging, long-term use of certain medications, certain types of health conditions, cancer treatment, consumption of alcohol and tobacco, and recreational drug use. It is crucial to address this condition because its symptoms can further aggravate and lead to complications such as tooth decay, mouth sores, mouth infections, poor nutritional absorption, and more. Diagnosis and treatment To zero down the cause of dry mouth, the doctor will go through one’s medical history as well as the medications the person is taking. They will also examine the mouth and might recommend some blood exams and imaging tests to determine the amount of saliva produced. If the doctor suspects that one’s dry mouth is a result of Sjogren’s syndrome, then they will extract a tiny sample of the tissue from the patient’s salivary glands and send it for further analysis. The cause of this condition defines its treatment. If the root cause of dry mouth is consistent use of medications, then the doctor will either adjust the dosage or switch to another variety of drugs.

Bacterial infection usually causes inflammation of the gums known as gingivitis. If the inflammation is not diagnosed and left untreated it can cause a serious infection known as periodontitis (also known as gum disease). Gingivitis and gum disease are major causes of tooth loss in the case of adults. While the leading cause of gum disease is plaque, some of the other factors that contribute to this condition include: Medical conditions There are certain conditions that affect the condition of one’s gums. This includes serious medical conditions that influence the immune system like cancer or HIV. Also, conditions like diabetes tend to affect a person’s ability to utilize sugar, this in turn increases the risk of risk of developing infections like cavities and periodontal disease. Lack of oral hygiene If one does not take care of his/her teeth by brushing and flossing regularly, it becomes easier to develop conditions like gingivitis. Certain medicines The oral health of a person is impacted because of certain medicines that tend to decrease in the flow of saliva. This is because saliva has a protective effect on gums and teeth. Some antianginal medications and anticonvulsant medications may cause abnormal growth of gum tissue leading to gum disease.